Project

Part:BBa_J54131

Designed by: Yusaku Nakashima   Group: iGEM06_Tokyo_Alliance   (2006-10-21)

BetI_regulated_promoter-GFP(A-3)

BetI_regulated_promoter-GFP(A-1)

Usage and Biology (added by CCA_San_Diego 2020)

Author: Ayush Agrawal, Noah Zhang

Summary: Provides an overview of the mechanism and its functionality.

Documentation:

Transcriptional factor betI (Betaine inhibitor) is a part of the TetR/AcR family of transcriptional regulators, acting as a repressor of glycine betaine synthesis from choline. BetI repressor protein remains bound to DNA during induction. Exposed to choline, betI forms a complex with DNA binding to a 20-bp-long sequence over betTp and betIp (Santos-Zavaleta, 2019).

References

[1] Alberto Santos-Zavaleta et. al. Nucleic Acids Research, Volume 47, Issue D1, 08 January 2019, Pages D212?D220, doi: https://doi.org/10.1093/nar/gky1077. PMID: 30395280. PMC: PMC6324031

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